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The ANNALS of the American Academy of Political and Social Science, Vol. 614, No. 1,
34-55 (2007)
DOI: 10.1177/0002716207305271
Genetic Configurations of Political Phenomena: New Theories, New Methods
Ira H. Carmen
Institute for Genomic Biology at the University of Illinois
Recent research by E. O. Wilson, Alford-Hibbing, Carmen, and others indicates that the competing social science paradigms of behavioralism and rational choice are in their last throes. Their salient weakness is insensitivity, bordering on ignorance, to politics as a biologically orchestrated phenomenon. More specifically, political scientists know precious little about either genetics or evolutionary dynamics. In this article, the author presents a new theory—sociogenomics—to replace the shopworn conceptions of yesterday's political science. The author then demonstrates how social scientists can employ the tools of molecular biology to flesh out the genes coding for baseline political attitudes and behaviors. The theory and methods of sociogenomics will serve to synthesize the social sciences with the natural sciences in a broader consilient framework, so that the laboratory of Darwinian investigation can become the laboratory of Aristotelian investigation.
Key Words: genetics twin studies magnetic resonance imaging sociogenomics consilience
References
- Abrahams, B.S., et al. 2005. Pathological aggression in "fierce" mice corrected by human nuclear receptor 2E1. Journal of Neuroscience 25 (27): 6263.[Abstract/Free Full Text]
- Adams, R.B., Jr., et al. 2003. Effects of gaze on amygdala sensitivity to anger and fear faces. Science 300:1536.[Free Full Text]
- Alford, J.R., C.L. Funk, and J.R. Hibbing. 2005. Are political orientations genetically transmitted? American Political Science Review 99:153.[ISI]
- Alford, J.R., and J.R. Hibbing. 2004. The origin of politics: An evolutionary theory of political behavior. Perspectives on Politics 2:707.
- ———. 2006. How are political orientations genetically transmitted? A research agenda? Paper presented at the Midwest Political Science Association Annual Meeting, Chicago.
- Barber, J.D. 1972. The presidential character. Englewood Cliffs, NJ: Prentice Hall.
- Barrett, T.B., et al. 2003. Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder. Molecular Psychiatry 8:546.
- Ben-Shahar, Y., et al. 2002. Influence of gene action across different time scales on behavior. Science 296:741.[Abstract/Free Full Text]
- Bouchard, T.J., Jr., and M. McGue. 2003. Genetic and environmental influences on human psychological differences. Journal of Neurobiology 54:4.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- Campbell, A., P.E. Converse, W.E. Miller, and D.E. Stokes. 1964. The American voter. New York: Wiley.
- Carmen, I.H. 2004. Politics in the laboratory: The constitution of human genomics. Madison: University of Wisconsin Press.
- ———. 2007. From genes, to mind, to politics: Finding the yellow brick empirical road. Paper presented at the Midwest Political Science Association Annual Meeting, Chicago.
- Caspi, A., et al. 2002. Role of genotype in the cycle of violence in maltreated children. Science 297:851.[Abstract/Free Full Text]
- ———. 2003. Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science 301:386.[Abstract/Free Full Text]
- de Quervain, D., et al. 2004. The neural basis of altruistic punishment. Science 305:1254.[Abstract/Free Full Text]
- Eaves, L., et al. 1999. Comparing the biological and cultural inheritance of personality and social attitudes in the Virginia 30,000 study of twins and their relatives. Twin Research 2:62.[CrossRef][Medline]
[Order article via Infotrieve]
- Eaves, L.J., and H.J. Eysenck. 1974. Genetics and the development of social attitudes. Nature 249:288.[CrossRef][Medline]
[Order article via Infotrieve]
- Egan, M.F., et al. 2001. Effect of COMT val 108/158 met genotype on frontal lobe function and risk for schizophrenia. Proceedings of the National Academy of Sciences 98:6917.[Abstract/Free Full Text]
- Francis, D., et al. 1999. Nanogenomic transmission across generations of maternal behavior and stress responses in the rat. Science 286:1155.[Abstract/Free Full Text]
- Freedman, J. 2005. This is your brain on politics. New York Times, January 18, p. A21.
- Gibbons, A. 2004. Tracking the evolutionary history of a "warrior" gene. Science 304:818.
- Glimcher, P.W., and A. Rustichini. 2004. Neuroeconomics: The consilience of brain and decision. Science 306:447.[Abstract/Free Full Text]
- Greenberg, J., and E. Jonas. 2003. Psychological motives and political orientation—The left, the right, and the rigid: Comment on Jost et al. (2003). Psychological Bulletin 129:376.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- Hamer, D. 2004. The God gene. New York: Doubleday.
- Hamer, D., et al. 1993. A linkage between DNA markers on the X chromosome and male sexual orientation. Science 261:321.[Abstract/Free Full Text]
- Hamer, D., and P. Copeland. 1998. Living with our genes. New York: Anchor.
- Hammock, E.A.D., and L.J. Young. 2005. Microsatellite instability generates diversity in brain and sociobehavioral traits. Science 308:1630.[Abstract/Free Full Text]
- Hariri, A.R., et al. 2002. Serotonin transporter genetic variation and the response of the human amygdala. Science 297:400.[Abstract/Free Full Text]
- Hsu, M., et al. 2005. Neural systems responding to degrees of uncertainty in human decision-making. Science 310:1680.[Abstract/Free Full Text]
- Hughes, C., et al. 2005. Origins of individual differences in theory of mind: From nature to nurture? Child Development 76:356.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- Jacobsen, L.K., et al. 2000. Prediction of dopamine transporter binding availability by genotype: A preliminary report. American Journal of Psychiatry 157:1700.[Abstract/Free Full Text]
- Jost, J.T., et al. 2003. Political conservatism as motivated social cognition. Psychological Bulletin 129:339.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- King-Casas, B., et al. 2005. Getting to know you: Reputation and trust in a two-person economic exchange. Science 308:78.[Abstract/Free Full Text]
- Knoch, D., et al. 2006. Diminishing reciprocal fairness by disrupting the right prefrontal cortex. Science 314:829.[Abstract/Free Full Text]
- Lander, E.S., and N.J. Schork. 1994. Genetic dissection of complex traits. Science 265:2037.[Abstract/Free Full Text]
- Lee, H.-J., et al. 2003. Allelic variants interaction of dopamine receptor D4 polymorphism correlate with personality traits in young Korean female population. American Journal of Medical Genetics Part B, 118B:76.
- Lemery, K.S., and L. Doelger. 2005. Genetic vulnerabilities to the development of psychopathology. In Development of psychopathology, ed. B. L. Hankin and J. R. Z. Abela. Thousand Oaks, CA: Sage.
- Lesch, K.-P., et al. 1996. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory system. Science 274:1527.[Abstract/Free Full Text]
- Loomis, W.F., and P.W. Sternberg. 1995. Genetic networks. Science 269:649.[Free Full Text]
- Lumsden, C.J., and E.O. Wilson. 1981. Genes, mind, and culture. Cambridge, MA: Harvard University Press.
- Lykken, D., and A. Tellegen. 1996. Happiness is a stochastic phenomenon. Psychological Science 7:186.[CrossRef][ISI]
- Martin, N.G., et al. 1986. Transmission of social attitudes. Proceedings of the National Academy of Sciences 83:4364.[Abstract/Free Full Text]
- McCourt, K., et al. 1999. Authoritarianism revisited: Genetic and environmental influence examined in twins reared apart and together. Personality of Individual Differences 27:985.[CrossRef]
- McDermott, R. 2004. The feeling of rationality: The meaning of neuroscientific advances for political science. Perspectives on Politics 2:691.
- Meng, H., et al. 2005. DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proceedings of the National Academy of Sciences 102:17053.[Abstract/Free Full Text]
- Meyer-Lindenberg, A., et al. 2006. Neural mechanisms of genetic risk for impulsivity and violence in humans. Proceedings of the National Academy of Sciences 103:6269.[Abstract/Free Full Text]
- Millet, B., et al. 2003. Association between the dopamine receptor D4 (DRD4) gene and obsessive-compulsive disorder. American Journal of Medical Genetics 116B:55.
- Olson, S. 2002. Seeking the signs of selection. Science 298:1324.[Free Full Text]
- Plomin, R., et al. 1994. The genetic basis of complex human behaviors. Science 264:1733.[Abstract/Free Full Text]
- Ridley, M. 2000. Genome. New York: Perennial.
- Rilling, J.K., et al. 2002. A neural basis for social cooperation. Neuron 35:395.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- Robins, R.W. 2005. The nature of personality: Genes, culture, and national character. Science 310:62.[Abstract/Free Full Text]
- Robinson, G. 2002. Sociogenomics takes flight. Science 297:204.[Free Full Text]
- Rossiter, C. 1962. Conservatism in America. 2nd ed. New York: Vintage.
- Rowe, D.C., et al. 1998. The relation of the dopamine transporter gene (DAT1) to symptoms of internalizing disorders in children. Behavior Genetics 28:215.
- Rushton, J.P., C.H. Littlefield, and C.J. Lumsden. 1986. Gene-culture coevolution of complex social behavior: Human altruism and mate choice. Proceedings of the National Academy of Sciences 83:7340.[Abstract/Free Full Text]
- Sanfey, A.G., et al. 2003. The neural basis of economic decision-making in the ultimate game. Science 300:1755.[Abstract/Free Full Text]
- Schubert, G. 1965. The judicial mind. Evanston, IL: Northwestern University Press.
- Schwartz, C.E., et al. 2003. Inhibited and uninhibited infants "grown up": Adult amygdalar response to novelty. Science 300:1952.[Abstract/Free Full Text]
- Segal, J.A., and H.J. Spaeth. 1993. The Supreme Court and the attitudinal model. Cambridge: Cambridge University Press.
- Shumyatsky, G.P., et al. 2005. Stathmin, a gene enriched in the amygdala, controls both learned and innate fear. Cell 123:697.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- Singer, T., et al. 2004. Brain responses to the acquired moral status of faces. Neuron 41:653.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- ———. 2006. Empathetic neural responses are modulated by the perceived fairness of others. Nature 439:466.[CrossRef][Medline]
[Order article via Infotrieve]
- Smoller, J.W., et al. 2003. Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibition. Biological Psychiatry 54:1376.
- Sokolowski, M.B. 2002. Social eating for stress. Nature 419:893.[CrossRef][Medline]
[Order article via Infotrieve]
- Tellegen, A., et al. 1988. Personality similarity in twins reared apart and together. Journal of Personality and Social Psychology 54:1031.[CrossRef][ISI][Medline]
[Order article via Infotrieve]
- Tetlock, P.E. 1983. Cognitive style and political ideology. Journal of Personality and Social Psychology 45:118.[CrossRef][ISI]
- ———. 1984. Cognitive style and political belief systems in the British House of Commons. Journal of Personality and Social Psychology 46:365.[CrossRef][ISI]
- Whitfield, C.W., et al. 2003. Gene expression profiles in the brain predict behavior in individual honey bees. Science 302:296.[Abstract/Free Full Text]
- Wilson, E.O. 1999. Consilience. New York: Vintage.
- Zhang, X., et al. 2005. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45:11.[CrossRef][ISI][Medline]
[Order article via Infotrieve]

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J. R. Alford and J. R. Hibbing
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The ANNALS of the American Academy of Political and Social Science,
November 1, 2007;
614(1):
196 - 212.
[Abstract]
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